An Overview of the Genetic Architecture of the Quantitative Traits

Genetic architecture of the quantitative traits is an important aspect for understanding the sustained response of selection and also for predicting the disease risk.  In regards to the distribution of effect of variants underlying the quantitative traits, Fisher (1918) proposed a simple explanation, termed as the infinitesimal model, where the quantitative traits are composed by … Continue reading An Overview of the Genetic Architecture of the Quantitative Traits

An Overview of the Determinant of the Genomic Diversity

Genetic diversity provides variations in which that selection can act upon, and it determines the response of population towards environmental change. Therefore, knowledge in genetic diversity is crucial for developing breeding strategies and also for the management of endangered species. Understanding the determinant genetic diversity is also essential for resolving the long-standing riddle in population … Continue reading An Overview of the Determinant of the Genomic Diversity

Mutation Rate Variation: An Evolutionary, Observational and Experimental Review

Mutation plays a pivotal role in evolution, as it generates diversity to fuel the selection processes. In more practical sense, animal response to artificial selection and the genetic basis of human disease are two among fields where it can be elucidated better by understanding mutation rate affecting genetic variation (Knightley & Halligan, 2009). It is … Continue reading Mutation Rate Variation: An Evolutionary, Observational and Experimental Review

Molecular Genetics Application in Agricultural Species Improvement

Pardon, for leaving this blog for a quite a while, I am busy preparing my master degree in Edinburgh which will be commenced this September. I will study Quantitative Genomics which require me to have a strong mathematical thinking. This essay is a summary of one preparatory reading for the courses. *Finger crossed Human have … Continue reading Molecular Genetics Application in Agricultural Species Improvement

Tugas Mingguan Genetika Pelatnas 3

Pada tugas genetika kali ini anda akan melakukan simulasi serangkaian fenomena mikroevolusi  dan kaitannya dengan dinamika frekuensi suatu alel. Gunakan tautan dibawah ini untuk melakukan simulasi tersebut http://www.radford.edu/~rsheehy/Gen_flash/popgen/ Pada simulasi ini anda akan melakukan analisis 5 populasi pada suatu gen yang memiliki 2 alel A1 dan A2 yang proporsinya setimbang. Proses mikroevolusi akan mengubah frekuensi … Continue reading Tugas Mingguan Genetika Pelatnas 3

Satiating Signal from Brain Regulates Feeding: Neuroscience and Genetic perspective for understanding obesity

Obesity is becoming a serious global threat nowadays. Combination lack of exercise and regular comsumption of heavy calorie meals are two major factor that people put blame on. However, there is also genetic factor that contribute to obesity, and study in this realm is still inadequate. Study conducted by Lagerlöf in Science (March, 2016) shed … Continue reading Satiating Signal from Brain Regulates Feeding: Neuroscience and Genetic perspective for understanding obesity